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ST14 Antibody - middle region: FITC (ARP48057_P050-FITC)

Product Specifications

Gene Name

Suppression of tumorigenicity 14 (colon carcinoma)

Gene Aliases

HAI, CAP3, MTSP1, SNC19, ARCI11, MT-SP1, PRSS14, TADG15, TMPRSS14

Gene ID

6768

Swiss Prot

Q9Y5Y6

Accession Number

NP_068813

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ST14

Target

ST14 is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.

Partner Proteins

UBC; RGS16; PDGFC; CDCP1; SPINT1; F2RL1; PLAU; HGF

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 92%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 92%; Rat: 93%; Zebrafish: 75%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

95kDa

Shipping Conditions

Wet Ice

Protein Length

855

NCBI Gene Symbol

ST14

Protein Name

Suppressor of tumorigenicity 14 protein

Nucleotide Accession Number

NM_021978

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