YWHAZ Antibody - C-terminal region: Biotin (ARP48046_T100-Biotin)
Product Specifications
Gene Name
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
Gene Aliases
HEL4, YWHAD, KCIP-1, HEL-S-3, POPCHAS, HEL-S-93, 14-3-3-zeta
Gene ID
7534
Swiss Prot
P63104
Accession Number
NP_003397
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human YWHAZ
Target
YWHAZ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for this gene.
Partner Proteins
FUS; UBC; HUWE1; MAPT; DTL; MAPK8; SGK1; ABL1; TSC2; DDIT4; SIK3; SIK2; SUMO2; STAU1; IRS4; MDM2; WWOX; YWHAZ; SNRPF; SNRPE; SLC9A3R1; LDHB; SFN; PFAS; PAK2; ERP44; MAPRE1; FERMT2; YWHAQ; PRMT5; YWHAH; YWHAG; VCL; UBE2V1; TGM2; EIF5; ECHS1; CAPNS1; ZFYVE1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
28kDa
Shipping Conditions
Wet Ice
Protein Length
245
NCBI Gene Symbol
YWHAZ
Protein Name
14-3-3 protein zeta/delta
Nucleotide Accession Number
NM_003406
Curated Selection
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