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YWHAZ Antibody - C-terminal region: Biotin (ARP48046_T100-Biotin)

Product Specifications

Gene Name

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide

Gene Aliases

HEL4, YWHAD, KCIP-1, HEL-S-3, POPCHAS, HEL-S-93, 14-3-3-zeta

Gene ID

7534

Swiss Prot

P63104

Accession Number

NP_003397

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human YWHAZ

Target

YWHAZ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for this gene.

Partner Proteins

FUS; UBC; HUWE1; MAPT; DTL; MAPK8; SGK1; ABL1; TSC2; DDIT4; SIK3; SIK2; SUMO2; STAU1; IRS4; MDM2; WWOX; YWHAZ; SNRPF; SNRPE; SLC9A3R1; LDHB; SFN; PFAS; PAK2; ERP44; MAPRE1; FERMT2; YWHAQ; PRMT5; YWHAH; YWHAG; VCL; UBE2V1; TGM2; EIF5; ECHS1; CAPNS1; ZFYVE1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

28kDa

Shipping Conditions

Wet Ice

Protein Length

245

NCBI Gene Symbol

YWHAZ

Protein Name

14-3-3 protein zeta/delta

Nucleotide Accession Number

NM_003406

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