REC8 Antibody - N-terminal region : FITC (ARP48037_P050-FITC)
Product Specifications
Gene Name
REC8 meiotic recombination protein
Gene Aliases
Rec8p, REC8L1, HR21spB
Gene ID
9985
Swiss Prot
O95072
Accession Number
NP_005123
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human REC8
Target
This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.
Partner Proteins
SYCP3; SMC3; SMC1A
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
REC8 is supported by BioGPS gene expression data to be expressed in 721_B
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
62kDa
References & Citations
Xu, H., (2005) Dev. Cell 8 (6), 949-961
Shipping Conditions
Wet Ice
Protein Length
547
NCBI Gene Symbol
REC8
NCBI GB Accession Number
REC8
Host or Source
Rabbit
Protein Name
Meiotic recombination protein REC8 homolog
Nucleotide Accession Number
NM_005132
Peptide Sequence
QLQIGVIRVYSQQCQYLVEDIQHILERLHRAQLQIRIDMETELPSLLLPN
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