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REC8 Antibody - N-terminal region : Biotin (ARP48037_P050-Biotin)

Product Specifications

Gene Name

REC8 meiotic recombination protein

Gene Aliases

Rec8p, REC8L1, HR21spB

Gene ID

9985

Swiss Prot

O95072

Accession Number

NP_005123

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human REC8

Target

This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.

Partner Proteins

SYCP3; SMC3; SMC1A

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

REC8 is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

62kDa

References & Citations

Xu, H., (2005) Dev. Cell 8 (6), 949-961

Shipping Conditions

Wet Ice

Protein Length

547

NCBI Gene Symbol

REC8

NCBI GB Accession Number

REC8

Host or Source

Rabbit

Protein Name

Meiotic recombination protein REC8 homolog

Nucleotide Accession Number

NM_005132

Peptide Sequence

QLQIGVIRVYSQQCQYLVEDIQHILERLHRAQLQIRIDMETELPSLLLPN

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