NR0B1 Antibody - middle region: FITC (ARP48005_P050-FITC)
Product Specifications
Gene Name
Nuclear receptor subfamily 0, group B, member 1
Gene Aliases
AHC, AHX, DSS, GTD, HHG, AHCH, DAX1, DAX-1, NROB1, SRXY2
Gene ID
190
Swiss Prot
P51843
Accession Number
NP_000466
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human NR0B1
Target
NR0B1 is a protein that contains a DNA-binding domain. The protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in its gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.
Partner Proteins
NR5A1; ESRRG; RORA; RNF31; UBC; NR3C1; ESRRA; SNW1; PPARG; POU5F1; PGR; AR; COPS2; NRIP1; ESR2; SREBF1; ESR1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
52kDa
Shipping Conditions
Wet Ice
Protein Length
470
NCBI Gene Symbol
NR0B1
Protein Name
Nuclear receptor subfamily 0 group B member 1
Nucleotide Accession Number
NM_000475
Curated Selection
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