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SETD2 Antibody - N-terminal region : HRP (ARP47617_T100-HRP)

Product Specifications

Gene Name

SET domain containing 2

Gene Aliases

LLS, HYPB, SET2, HIF-1, HIP-1, KMT3A, HBP231, HSPC069, p231HBP

Gene ID

29072

Swiss Prot

Q9BYW2

Accession Number

AAH72440

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SETD2

Target

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. SETD2 is a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs.

Partner Proteins

CLK2; SOX2; CBX8; HCVgp1; SIAH2; SMAD3; CIC; ATXN1; ELAVL1; UBC; SETD2; HIST1H3A; POLR2A; TP53; IWS1; HTT

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

SETD2 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Dog: 86%; Horse: 86%; Human: 100%; Mouse: 83%; Rat: 85%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

97kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-SETD2 (ARP47617_T100-HRP) antibody

Protein Length

891

NCBI Gene Symbol

SETD2

NCBI GB Accession Number

SETD2

Host or Source

Rabbit

Protein Name

Histone-lysine N-methyltransferase SETD2

Nucleotide Accession Number

NM_014159

Peptide Sequence

SDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKSEDLGKPSRSKTD

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