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SETD2 Antibody - N-terminal region : HRP (ARP47617_T100-HRP)

Selected Variant

ARP47617_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

SET domain containing 2

Gene Aliases

LLS, HYPB, SET2, HIF-1, HIP-1, KMT3A, HBP231, HSPC069, p231HBP

Gene ID

29072

Swiss Prot

Q9BYW2

Accession Number

AAH72440

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SETD2

Target

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. SETD2 is a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs.

Partner Proteins

CLK2; SOX2; CBX8; HCVgp1; SIAH2; SMAD3; CIC; ATXN1; ELAVL1; UBC; SETD2; HIST1H3A; POLR2A; TP53; IWS1; HTT

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

SETD2 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Dog: 86%; Horse: 86%; Human: 100%; Mouse: 83%; Rat: 85%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

97kDa

Shipping Conditions

Wet Ice

Protein Length

891

NCBI Gene Symbol

SETD2

NCBI GB Accession Number

SETD2

Host or Source

Rabbit

Protein Name

Histone-lysine N-methyltransferase SETD2

Nucleotide Accession Number

NM_014159

Peptide Sequence

SDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKSEDLGKPSRSKTD

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