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PA2G4 Antibody - middle region : HRP (ARP47602_T100-HRP)

Product Specifications

Gene Name

Proliferation-associated 2G4, 38kDa

Gene Aliases

EBP1, HG4-1, p38-2G4

Gene ID

5036

Swiss Prot

Q9UQ80

Accession Number

NP_006182

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PA2G4

Target

PA2G4 is an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells.

Partner Proteins

DHX9; PKN1; NPM1; NCL; LAMB1; HSPA1B; HNRNPA2B1; ACTB; ERBB3; DDX21; VIM; UBC; RNF20; SUMO2; SUMO3; MDM2; STUB1; HSPA4; YBX1; NMT1; MAP2; KRT17; FAU; RPL23A; RPS27L; EIF3K; DIMT1; NELFB; IGF2BP3; G3BP1; EXOSC5; HMGA2; HMGA1; EEF2K; UBL4A; ITGA4; FN1; IGF2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Sample Type

PA2G4 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 90%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

44kDa

References & Citations

Zhang, Y., (2005) Proc. Natl. Acad. Sci. U.S.A. 102 (28), 9890-9895

Shipping Conditions

Wet Ice

Protein Length

394

NCBI Gene Symbol

PA2G4

NCBI GB Accession Number

PA2G4

Host or Source

Rabbit

Protein Name

Proliferation-associated protein 2G4

Nucleotide Accession Number

NM_006191

Peptide Sequence

NCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVD

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