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SMC3 Antibody - N-terminal region : FITC (ARP47592_P050-FITC)

Product Specifications

Gene Name

Structural maintenance of chromosomes 3

Gene Aliases

BAM, BMH, HCAP, CDLS3, CSPG6, SMC3L1

Gene ID

9126

Swiss Prot

Q9UQE7

Accession Number

NP_005436

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SMC3

Target

SMC3 belongs to the SMC3 subfamily of SMC proteins. SMC3 occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation.

Partner Proteins

SUMO2; UBC; RPA3; RPA2; RPA1; SUZ12; EED; RNF2; FBXO6; ANKRD28; HDAC11; HDAC8; HDAC9; SOX2; RAD21; CDCA5; PDS5A; WAPAL; MMS19; METTL21B; NOTCH1; SMC1A; SFPQ; HNRNPM; NSMCE2; UBD; COPS5; COPS6; CUL2; CUL3; NEDD8; CDK2; FBXO25; MECP2; NIPBL; CDK8; SUPT5H; P

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that SMC3 is expressed in COLO205

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

141kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-SMC3 (ARP47592_P050-FITC) antibody

Protein Length

1217

NCBI Gene Symbol

SMC3

NCBI GB Accession Number

SMC3

Host or Source

Rabbit

Protein Name

Structural maintenance of chromosomes protein 3

Nucleotide Accession Number

NM_005445

Peptide Sequence

KWDKMRRALEYTIYNQELNETRAKLDELSAKRETSGEKSRQLRDAQQDAR

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