SMC3 Antibody - N-terminal region : Biotin (ARP47592_P050-Biotin)
Product Specifications
Gene Name
Structural maintenance of chromosomes 3
Gene Aliases
BAM, BMH, HCAP, CDLS3, CSPG6, SMC3L1
Gene ID
9126
Swiss Prot
Q9UQE7
Accession Number
NP_005436
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human SMC3
Target
SMC3 belongs to the SMC3 subfamily of SMC proteins. SMC3 occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation.
Partner Proteins
SUMO2; UBC; RPA3; RPA2; RPA1; SUZ12; EED; RNF2; FBXO6; ANKRD28; HDAC11; HDAC8; HDAC9; SOX2; RAD21; CDCA5; PDS5A; WAPAL; MMS19; METTL21B; NOTCH1; SMC1A; SFPQ; HNRNPM; NSMCE2; UBD; COPS5; COPS6; CUL2; CUL3; NEDD8; CDK2; FBXO25; MECP2; NIPBL; CDK8; SUPT5H; P
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
There is BioGPS gene expression data showing that SMC3 is expressed in COLO205
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
141kDa
Shipping Conditions
Wet Ice
Protein Length
1217
NCBI Gene Symbol
SMC3
NCBI GB Accession Number
SMC3
Host or Source
Rabbit
Protein Name
Structural maintenance of chromosomes protein 3
Nucleotide Accession Number
NM_005445
Peptide Sequence
KWDKMRRALEYTIYNQELNETRAKLDELSAKRETSGEKSRQLRDAQQDAR
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