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SMC3 Antibody - C-terminal region : HRP (ARP47590_P050-HRP)

Selected Variant

ARP47590_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Structural maintenance of chromosomes 3

Gene Aliases

BAM, BMH, HCAP, CDLS3, CSPG6, SMC3L1

Gene ID

9126

Swiss Prot

Q9UQE7

Accession Number

AAD32447

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human SMC3

Target

SMC3 belongs to the SMC3 subfamily of SMC proteins. SMC3 occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation.

Partner Proteins

SUMO2; UBC; RPA3; RPA2; RPA1; SUZ12; EED; RNF2; FBXO6; ANKRD28; HDAC11; HDAC8; HDAC9; SOX2; RAD21; CDCA5; PDS5A; WAPAL; MMS19; METTL21B; NOTCH1; SMC1A; SFPQ; HNRNPM; NSMCE2; UBD; COPS5; COPS6; CUL2; CUL3; NEDD8; CDK2; FBXO25; MECP2; NIPBL; CDK8; SUPT5H; P

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that SMC3 is expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

74kDa

Shipping Conditions

Wet Ice

Protein Length

681

NCBI Gene Symbol

SMC3

NCBI GB Accession Number

SMC3

Host or Source

Rabbit

Protein Name

Structural maintenance of chromosomes protein 3

Nucleotide Accession Number

NM_005445

Peptide Sequence

GKATLVMKKGDVEGSQSQDEGEGSGESERGSGSQSSVPSVDQFTGVGIRV

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