FTO Antibody - middle region : Biotin (ARP47474_P050-Biotin)
Selected Variant
ARP47474_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Fat mass and obesity associated
Gene Aliases
GDFD, ALKBH9, BMIQ14
Gene ID
79068
Swiss Prot
Q9C0B1
Accession Number
NP_001073901
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human FTO
Target
The exact function of this gene is not know. Studies in mice suggest that it may be involved in nucleic acid demethylation, and that its mRNA level is regulated by feeding and fasting. Genomewide association studies of type 2 diabetes indicate this gene as a diabetes susceptibility locus. Mutation in this gene has been associated with growth retardation, developmental delay, coarse facies, and early death.
Partner Proteins
UBC; SUMO1; NEDD8; BCCIP; CNDP2; DAK; NDRG1; NPEPPS; SLC9A3R1; CTSA; PEPD; MVD; LDHB; LDHA; EEF2; CKB
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Dog: 86%; Guinea Pig: 100%; Horse: 79%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
58kDa
Shipping Conditions
Wet Ice
Protein Length
505
NCBI Gene Symbol
FTO
NCBI GB Accession Number
FTO
Host or Source
Rabbit
Protein Name
Alpha-ketoglutarate-dependent dioxygenase FTO
Nucleotide Accession Number
NM_001080432
Peptide Sequence
WWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTA
Price
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