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ADCY10 Antibody : Biotin (ARP47448_P050-Biotin)

Selected Variant

ARP47448_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Adenylate cyclase 10 (soluble)

Gene Aliases

SAC, HCA2, SACI, Sacy, hsAC, HEL-S-7a

Gene ID

55811

Swiss Prot

Q96PN6

Accession Number

NP_060887

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the following sequence LMFVDISGFTAMTEKFSSAMYMDRGAEQLVEILNYHISAIVEKVLIFGGD

Target

The protein encoded by this gene belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction. Genetic variations in this gene are associated with absorptive hypercalciuria type 2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

PTGIR; SSTR5

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

187 kDa

Shipping Conditions

Wet Ice

Protein Length

1610

NCBI Gene Symbol

ADCY10

NCBI GB Accession Number

ADCY10

Host or Source

Rabbit

Protein Name

Adenylate cyclase type 10

Nucleotide Accession Number

NM_001167749

Peptide Sequence

LMFVDISGFTAMTEKFSSAMYMDRGAEQLVEILNYHISAIVEKVLIFGGD

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