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KIRREL1 Antibody - middle region : HRP (ARP47408_P050-HRP)

Product Specifications

Gene Name

Kirre like nephrin family adhesion molecule 1

Gene Aliases

NEPH1, KIRREL, NPHS23

Gene ID

55243

Swiss Prot

Q96J84

Accession Number

NP_060710

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human KIRREL

Target

NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762) . The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]) .[supplied by OMIM, Mar 2008]

Partner Proteins

UBC; SAV1; LATS1; GRB2; KIRREL; NPHS2; NPHS1; TJP1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

84kDa

References & Citations

Harita, Y., (2008) J. Biol. Chem. 283 (14), 9177-9186

Shipping Conditions

Wet Ice

Protein Length

757

NCBI Gene Symbol

KIRREL1

NCBI GB Accession Number

KIRREL1

Host or Source

Rabbit

Protein Name

Kin of IRRE-like protein 1

Nucleotide Accession Number

NM_018240

Peptide Sequence

FLEVGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPG

Frequently Asked Questions

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