Hsd17b12 Antibody - C-terminal region : FITC (ARP47217_P050-FITC)
Selected Variant
ARP47217_P050-FITC
Size: 100 µL
Product Specifications
Gene Aliases
KIK, Kik1, KIK-I, AI172963, 2610510O05Rik
Gene ID
56348
Swiss Prot
O70503
Accession Number
NP_062631
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Hsd17b12
Target
Hsd17b12 catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in females. Hsd17b12 also has 3-ketoacyl-CoA reductase activity, reducing both long chain 3-ketoacyl-CoAs and long chain fatty acyl-CoAs, suggesting a role in long fatty acid elongation.
Partner Proteins
Eed; DSK2; VPS9; NUB1; UBQLN1; SQSTM1; RAD23B; PSMD4; NBR1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 79%; Dog: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 79%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
35kDa
Shipping Conditions
Wet Ice
Protein Length
312
NCBI Gene Symbol
HSD17B12
NCBI GB Accession Number
Hsd17b12
Host or Source
Rabbit
Protein Name
Estradiol 17-beta-dehydrogenase 12
Nucleotide Accession Number
NM_019657
Peptide Sequence
SAETFVKSAIKTVGLQTRTTGYVIHSLMGSINSIMPRWMYFKIIMGFSKS
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