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GALNAC4S-6ST Antibody - middle region : FITC (ARP47193_P050-FITC)

Selected Variant

ARP47193_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15

Gene Aliases

BRAG, GALNAC4S-6ST

Gene ID

51363

Swiss Prot

Q7LFX5

Accession Number

NP_056976

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human GALNAC4S-6ST

Target

GALNAC4S-6ST is a sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc (4,6-SO (4) ) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc (4SO4) -GlcA (2SO4) -GalNAc (6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. GALNAC4S-6ST may also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression; however such results are unclear in vivo.

Partner Proteins

UBC; RRAGD; LYN; HCK

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

CHST15 is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

65kDa

References & Citations

Sawada, T., (2005) Carbohydr. Res. 340 (12), 1983-1996

Shipping Conditions

Wet Ice

Protein Length

561

NCBI Gene Symbol

CHST15

NCBI GB Accession Number

CHST15

Host or Source

Rabbit

Protein Name

Carbohydrate sulfotransferase 15

Nucleotide Accession Number

NM_015892

Peptide Sequence

YDNSTDGEPPFLTQDFIHAFQPNARLIVMLRDPVERLYSDYLYFASSNKS

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