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GALNAC4S-6ST Antibody - middle region : Biotin (ARP47193_P050-Biotin)

Product Specifications

Gene Name

Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15

Gene Aliases

BRAG, GALNAC4S-6ST

Gene ID

51363

Swiss Prot

Q7LFX5

Accession Number

NP_056976

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human GALNAC4S-6ST

Target

GALNAC4S-6ST is a sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc (4,6-SO (4) ) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc (4SO4) -GlcA (2SO4) -GalNAc (6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. GALNAC4S-6ST may also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression; however such results are unclear in vivo.

Partner Proteins

UBC; RRAGD; LYN; HCK

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

CHST15 is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

65kDa

References & Citations

Sawada, T., (2005) Carbohydr. Res. 340 (12), 1983-1996

Shipping Conditions

Wet Ice

Protein Length

561

NCBI Gene Symbol

CHST15

NCBI GB Accession Number

CHST15

Host or Source

Rabbit

Protein Name

Carbohydrate sulfotransferase 15

Nucleotide Accession Number

NM_015892

Peptide Sequence

YDNSTDGEPPFLTQDFIHAFQPNARLIVMLRDPVERLYSDYLYFASSNKS

Frequently Asked Questions

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