MBTPS2 Antibody: FITC (ARP47191_P050-FITC)
Product Specifications
Gene Name
Membrane-bound transcription factor peptidase, site 2
Gene Aliases
S2P, IFAP, KFSD, OI19, KFSDX, OLMSX, BRESEK
Gene ID
51360
Swiss Prot
O43462
Accession Number
NP_056968
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the following sequence LVVVVVGGWTVVYLTDLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTA
Target
This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome) ; IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.
Partner Proteins
UBC; ATF6B
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
57 kDa
Shipping Conditions
Wet Ice
Protein Length
519
NCBI Gene Symbol
MBTPS2
Protein Name
Membrane-bound transcription factor site-2 protease
Nucleotide Accession Number
NM_015884
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