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TNFRSF21 Antibody - N-terminal region : Biotin (ARP47029_P050-Biotin)

Product Specifications

Gene Name

Tumor necrosis factor receptor superfamily, member 21

Gene Aliases

DR6, CD358, BM-018

Gene ID

27242

Swiss Prot

O75509

Accession Number

NP_055267

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TNFRSF21

Target

TNFRSF21 is a member of the TNF-receptor superfamily. This receptor has been shown to activate¡¡NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of¡¡TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.

Partner Proteins

NSD1; CLIP3; ELAVL1; WASH2P; MATR3; STX11; TRADD

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

TNFRSF21 is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 93%; Horse: 93%; Human: 100%; Mouse: 91%; Rabbit: 93%; Rat: 91%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

68kDa

References & Citations

Norberg, A., (2006) Neurosci. Lett. 396 (2), 137-142

Shipping Conditions

Wet Ice

Protein Length

655

NCBI Gene Symbol

TNFRSF21

NCBI GB Accession Number

TNFRSF21

Host or Source

Rabbit

Protein Name

Tumor necrosis factor receptor superfamily member 21

Nucleotide Accession Number

NM_014452

Peptide Sequence

TTTAQPEQKASNLIGTYRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLRV

Frequently Asked Questions

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