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AFG3L2 Antibody - middle region : FITC (ARP46780_P050-FITC)

Product Specifications

Gene Name

AFG3 ATPase family gene 3-like 2 (S. cerevisiae)

Gene Aliases

OPA12, SCA28, SPAX5

Gene ID

10939

Swiss Prot

Q9Y4W6

Accession Number

NP_006787

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human AFG3L2

Target

AFG3L2 is a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. AFG3L2 gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.

Partner Proteins

SUMO2; UBC; SUZ12; RNF2; HIPK4; FBXO6; BTK; APP; MAPK8IP2; RAC2; ICT1; BECN1; CLN3; USP50; PHC2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

AFG3L2 is supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 79%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 85%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

88kDa

References & Citations

Banfi, S., (1999) Genomics 59 (1), 51-58

Shipping Conditions

Wet Ice

Protein Length

797

NCBI Gene Symbol

AFG3L2

NCBI GB Accession Number

AFG3L2

Host or Source

Rabbit

Protein Name

AFG3-like protein 2

Nucleotide Accession Number

NM_006796

Peptide Sequence

VNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVS

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