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AFG3L2 Antibody - middle region : Biotin (ARP46780_P050-Biotin)

Product Specifications

Gene Name

AFG3 ATPase family gene 3-like 2 (S. cerevisiae)

Gene Aliases

OPA12, SCA28, SPAX5

Gene ID

10939

Swiss Prot

Q9Y4W6

Accession Number

NP_006787

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human AFG3L2

Target

AFG3L2 is a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. AFG3L2 gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.

Partner Proteins

SUMO2; UBC; SUZ12; RNF2; HIPK4; FBXO6; BTK; APP; MAPK8IP2; RAC2; ICT1; BECN1; CLN3; USP50; PHC2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

AFG3L2 is supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 79%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 85%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

88kDa

References & Citations

Banfi, S., (1999) Genomics 59 (1), 51-58

Shipping Conditions

Wet Ice

Protein Length

797

NCBI Gene Symbol

AFG3L2

NCBI GB Accession Number

AFG3L2

Host or Source

Rabbit

Protein Name

AFG3-like protein 2

Nucleotide Accession Number

NM_006796

Peptide Sequence

VNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVS

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