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GCS1 Antibody - N-terminal region : HRP (ARP46708_P050-HRP)

Selected Variant

ARP46708_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Mannosyl-oligosaccharide glucosidase

Gene Aliases

DER7, GCS1, CDG2B, CWH41

Gene ID

7841

Swiss Prot

Q13724

Accession Number

NP_006293

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GCS1

Target

GCS1 is the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc (3) -Man (9) -GlcNAc (2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum.This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc (3) -Man (9) -GlcNAc (2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum.

Partner Proteins

HAUS2; CEP250; CEP57; AURKB; TP53; LGALS3BP; CDKN1A; CEP76; STAU1; SUMO1; UBC; NEDD8; env; vpr; UBL4A; NUP62; HNRNPR; TECR; RPS24; RPL31; RAP1B; RAB5A; HNRNPF; MYC; CHGB

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

92kDa

References & Citations

Hardt, B., (2003) Glycobiology 13 (3), 159-168

Shipping Conditions

Wet Ice

Protein Length

837

NCBI Gene Symbol

MOGS

NCBI GB Accession Number

MOGS

Host or Source

Rabbit

Protein Name

Mannosyl-oligosaccharide glucosidase

Nucleotide Accession Number

NM_006302

Peptide Sequence

GPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQ

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