GCS1 Antibody - N-terminal region : FITC (ARP46708_P050-FITC)
Product Specifications
Gene Name
Mannosyl-oligosaccharide glucosidase
Gene Aliases
DER7, GCS1, CDG2B, CWH41
Gene ID
7841
Swiss Prot
Q13724
Accession Number
NP_006293
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human GCS1
Target
GCS1 is the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc (3) -Man (9) -GlcNAc (2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum.This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc (3) -Man (9) -GlcNAc (2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum.
Partner Proteins
HAUS2; CEP250; CEP57; AURKB; TP53; LGALS3BP; CDKN1A; CEP76; STAU1; SUMO1; UBC; NEDD8; env; vpr; UBL4A; NUP62; HNRNPR; TECR; RPS24; RPL31; RAP1B; RAB5A; HNRNPF; MYC; CHGB
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
92kDa
References & Citations
Hardt, B., (2003) Glycobiology 13 (3), 159-168
Shipping Conditions
Wet Ice
Protein Length
837
NCBI Gene Symbol
MOGS
NCBI GB Accession Number
MOGS
Host or Source
Rabbit
Protein Name
Mannosyl-oligosaccharide glucosidase
Nucleotide Accession Number
NM_006302
Peptide Sequence
GPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQ
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