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ST3GAL4 Antibody - middle region : Biotin (ARP46703_P050-Biotin)

Product Specifications

Gene Name

ST3 beta-galactoside alpha-2,3-sialyltransferase 4

Gene Aliases

STZ, SAT3, ST-4, CGS23, SIAT4, NANTA3, SIAT4C, ST3GalIV, ST3GalA.2, gal-NAc6S

Gene ID

6484

Swiss Prot

Q6IBE6

Accession Number

NP_006269

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ST3GAL4

Target

It may catalyze the formation of the NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- or NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc-sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. It may be involved in the biosynthesis of the sialyl Lewis X determinant.Synthesis of alpha-2,3-linked sialic acid to Gal (beta-1,3) GalNAc is mediated by at least 3 distinct beta-galactoside alpha-2,3-sialyltransferases (EC 2.4.99.4), including ST3GAL4. In contrast, only a single gene encodes the beta-galactoside alpha-2,6-sialyltransferase (EC 2.4.99.1), ST6GAL1 (MIM 109675) (Chang et al., 1995 [PubMed 7655169]) .[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

UBC; ARHGDIA; CD8B

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

ST3GAL4 is supported by BioGPS gene expression data to be expressed in 721_B, HeLa, MCF7

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

37kDa

References & Citations

Higai, K., (2006) FEBS Lett. 580 (26), 6069-6075

Shipping Conditions

Wet Ice

Protein Length

329

NCBI Gene Symbol

ST3GAL4

NCBI GB Accession Number

ST3GAL4

Host or Source

Rabbit

Protein Name

SIAT4C protein EMBL CAG33139.1

Nucleotide Accession Number

NM_006278

Peptide Sequence

IKQKPTTGLLAITLALHLCDLVHIAGFGYPDAYNKKQTIHYYEQITLKSM

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