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ALDH6A1 Antibody - middle region : HRP (ARP46620_P050-HRP)

Selected Variant

ARP46620_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Aldehyde dehydrogenase 6 family, member A1

Gene Aliases

MMSDH, MMSADHA

Gene ID

4329

Swiss Prot

Q02252

Accession Number

NP_005580

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ALDH6A1

Target

ALDH6A1 plays a role in valine and pyrimidine metabolism. ALDH6A1 binds fatty acyl-CoA.This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.

Partner Proteins

UBC; LMO2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

54kDa

References & Citations

Kuiper, H., Cytogenet. Genome Res. 109 (4), 533 (2005)

Shipping Conditions

Wet Ice

Protein Length

535

NCBI Gene Symbol

ALDH6A1

NCBI GB Accession Number

ALDH6A1

Host or Source

Rabbit

Protein Name

Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial

Nucleotide Accession Number

NM_005589

Peptide Sequence

AVLVGEAKKWLPELVEHAKNLRVNAGDQPGADLGPLITPQAKERVCNLID

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