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ATP2A3 Antibody - middle region : Biotin (ARP46580_P050-Biotin)

Product Specifications

Gene Name

ATPase, Ca++ transporting, ubiquitous

Gene Aliases

SERCA3

Gene ID

489

Swiss Prot

Q93084

Accession Number

NP_005164

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ATP2A3

Target

ATP2A3 is one of the SERCA Ca (2+) -ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction.This gene encodes one of the SERCA Ca (2+) -ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms.

Partner Proteins

BCL2; UBC; BMI1; HDAC11; env; ATF2; CDK2; TCF3; IRS1; WRAP73

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

ATP2A3 is strongly supported by BioGPS gene expression data to be expressed in Jurkat, MCF7

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 86%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Rabbit: 77%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

109kDa

References & Citations

Korosec, B., (2008) Cancer Genet. Cytogenet. 181 (2), 112-118

Shipping Conditions

Wet Ice

Protein Length

999

NCBI Gene Symbol

ATP2A3

NCBI GB Accession Number

ATP2A3

Host or Source

Rabbit

Protein Name

Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

Nucleotide Accession Number

NM_005173

Peptide Sequence

LISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCS

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