TMPRSS11D Antibody - N-terminal region : FITC (ARP46418_T100-FITC)
Selected Variant
ARP46418_T100-FITC
Size: 100 µL
Product Specifications
Gene Name
Transmembrane protease, serine 11D
Gene Aliases
ASP, HAT
Gene ID
9407
Swiss Prot
O60235
Accession Number
NP_004253
Host
Rabbit
Reactivity
Human, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human TMPRSS11D
Target
TMPRSS11D is a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC, WB
Concentration
0.5 mg/ml
Homology
Guinea Pig: 79%; Horse: 79%; Human: 100%; Rabbit: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
46kDa
References & Citations
Matsushima, R., Am. J. Physiol. Lung Cell Mol. Physiol. 290 (2), L385-L395 (2006)
Shipping Conditions
Wet Ice
Protein Length
418
NCBI Gene Symbol
TMPRSS11D
NCBI GB Accession Number
TMPRSS11D
Host or Source
Rabbit
Protein Name
Transmembrane protease serine 11D
Nucleotide Accession Number
NM_004262
Peptide Sequence
RSSFQLLNVEYNSQLNSPATQEYRTLSGRIESLITKTFKESNLRNQFIRA
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