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TMPRSS11D Antibody - N-terminal region : FITC (ARP46418_T100-FITC)

Selected Variant

ARP46418_T100-FITC

Size: 100 µL

Product Specifications

Gene Name

Transmembrane protease, serine 11D

Gene Aliases

ASP, HAT

Gene ID

9407

Swiss Prot

O60235

Accession Number

NP_004253

Host

Rabbit

Reactivity

Human, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TMPRSS11D

Target

TMPRSS11D is a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Guinea Pig: 79%; Horse: 79%; Human: 100%; Rabbit: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

46kDa

References & Citations

Matsushima, R., Am. J. Physiol. Lung Cell Mol. Physiol. 290 (2), L385-L395 (2006)

Shipping Conditions

Wet Ice

Protein Length

418

NCBI Gene Symbol

TMPRSS11D

NCBI GB Accession Number

TMPRSS11D

Host or Source

Rabbit

Protein Name

Transmembrane protease serine 11D

Nucleotide Accession Number

NM_004262

Peptide Sequence

RSSFQLLNVEYNSQLNSPATQEYRTLSGRIESLITKTFKESNLRNQFIRA

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