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PIGQ Antibody - N-terminal region : Biotin (ARP46416_P050-Biotin)

Selected Variant

ARP46416_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Phosphatidylinositol glycan anchor biosynthesis, class Q

Gene Aliases

GPI1, DEE77, EIEE77, c407A10.1

Gene ID

9091

Swiss Prot

Q9BRB3

Accession Number

NP_004195

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PIGQ

Target

PIGQ is involved in the first step in glycosylphosphatidylinositol (GPI) -anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. PIGQ is a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI) .This gene is involved in the first step in glycosylphosphatidylinositol (GPI) -anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI) .

Partner Proteins

SMAD1; UBC; PIGC; PIGH; PIGA; PIGP

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 86%; Guinea Pig: 79%; Horse: 93%; Human: 100%; Mouse: 79%; Rabbit: 93%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

65kDa

References & Citations

Martin, J., (2004) Nature 432 (7020), 988-994

Shipping Conditions

Wet Ice

Protein Length

581

NCBI Gene Symbol

PIGQ

NCBI GB Accession Number

PIGQ

Host or Source

Rabbit

Protein Name

CDNA, FLJ95129, highly similar to Homo sapiens phosphatidylinositol glycan, class Q (PIGQ), transcript variant 2, mRNA EMBL BAG36993.1

Nucleotide Accession Number

NM_004204

Peptide Sequence

PTVLPDRQAGATTASTGGLAAVFDTVARSEVLFRSDRFDEGPVRLSHWQS

Subunit

Q

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