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ST3GAL5 Antibody - N-terminal region : FITC (ARP46385_T100-FITC)

Selected Variant

ARP46385_T100-FITC

Size: 100 µL

Product Specifications

Gene Name

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

Gene Aliases

SATI, SIAT9, SPDRS, ST3GalV, SIATGM3S, ST3Gal V

Gene ID

8869

Swiss Prot

Q6NZX4

Accession Number

NP_003887

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Horse, Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ST3GAL5

Target

Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. ST3GAL5 is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. It is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in its gene has been associated with Amish infantile epilepsy syndrome.Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus.

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Goat: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

48kDa

References & Citations

Chung, T.W., (2005) Glycobiology 15 (3), 233-244

Shipping Conditions

Wet Ice

Protein Length

418

NCBI Gene Symbol

ST3GAL5

NCBI GB Accession Number

ST3GAL5

Host or Source

Rabbit

Protein Name

Lactosylceramide alpha-2,3-sialyltransferase

Nucleotide Accession Number

NM_003896

Peptide Sequence

DSEAESKYDPPFGFRKFSSKVQTLLELLPEHDLPEHLKAKTCRRCVVIGS

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