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NMT1 Antibody - N-terminal region : HRP (ARP46299_P050-HRP)

Selected Variant

ARP46299_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

N-myristoyltransferase 1

Gene Aliases

NMT

Gene ID

4836

Swiss Prot

P30419

Accession Number

NP_066565

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NMT1

Target

Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1) .

Partner Proteins

C14orf166; RTCB; DIMT1; NELFB; EDC4; IGF2BP3; PDCD6; POLR1C; EIF2B2; EIF2B3; YBX3; RPL38; RPL23A; RPL19; RFC4; QARS; PA2G4; YBX1; HNRNPM; MRE11A; MAP2; ILF2; IARS; HNRNPU; FLII; FKBP3; DYNC1LI2; DHX9; DDX1; ABCF1; nef; UBC; CSNK2A1; gag; ARL5A; CABP2; MAR

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

NMT1 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

57kDa

References & Citations

Takamune, N., (2008) Microbes Infect. 10 (2), 143-150

Shipping Conditions

Wet Ice

Protein Length

496

NCBI Gene Symbol

NMT1

NCBI GB Accession Number

NMT1

Host or Source

Rabbit

Protein Name

Glycylpeptide N-tetradecanoyltransferase 1

Nucleotide Accession Number

NM_021079

Peptide Sequence

TMEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFT

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