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NMT1 Antibody - N-terminal region : Biotin (ARP46299_P050-Biotin)

Selected Variant

ARP46299_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

N-myristoyltransferase 1

Gene Aliases

NMT

Gene ID

4836

Swiss Prot

P30419

Accession Number

NP_066565

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NMT1

Target

Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1) .

Partner Proteins

C14orf166; RTCB; DIMT1; NELFB; EDC4; IGF2BP3; PDCD6; POLR1C; EIF2B2; EIF2B3; YBX3; RPL38; RPL23A; RPL19; RFC4; QARS; PA2G4; YBX1; HNRNPM; MRE11A; MAP2; ILF2; IARS; HNRNPU; FLII; FKBP3; DYNC1LI2; DHX9; DDX1; ABCF1; nef; UBC; CSNK2A1; gag; ARL5A; CABP2; MAR

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

NMT1 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

57kDa

References & Citations

Takamune, N., (2008) Microbes Infect. 10 (2), 143-150

Shipping Conditions

Wet Ice

Protein Length

496

NCBI Gene Symbol

NMT1

NCBI GB Accession Number

NMT1

Host or Source

Rabbit

Protein Name

Glycylpeptide N-tetradecanoyltransferase 1

Nucleotide Accession Number

NM_021079

Peptide Sequence

TMEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFT

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