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MRPL39 Antibody - N-terminal region : Biotin (ARP46256_P050-Biotin)

Product Specifications

Gene Name

Mitochondrial ribosomal protein L39

Gene Aliases

L5mt, L39mt, MRPL5, RPML5, MRP-L5, PRED22, PRED66, MSTP003, C21orf92

Gene ID

54148

Swiss Prot

Q9NYK5

Accession Number

NP_059142

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MRPL39

Target

Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. MRPL39 is a 39S subunit protein. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q.

Partner Proteins

TP53; UBC; SOX2; NPM1; MRPL55; MRPL52; MRPL24; MRPL44; MRPL9; MRPL11; MRPL32; MRPL38; MRPL40; MRPS9; MRPL14; MARC1; TSR1; MRPL37; MRPL15; MRPL13; MRPL3; MRPL19; LAMTOR3; NONO; ILF3; ICT1; DLST; MRPL49; CAND1; CUL3; TCF3; USP32; PAN2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 92%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

39kDa

References & Citations

Zhang, Z. (2003) Genomics 81 (5), 468-480

Shipping Conditions

Wet Ice

Protein Length

338

NCBI Gene Symbol

MRPL39

NCBI GB Accession Number

MRPL39

Host or Source

Rabbit

Protein Name

39S ribosomal protein L39, mitochondrial

Nucleotide Accession Number

NM_017446

Peptide Sequence

TELTEMRNDLFNKEKARQLSLTPRTEKIEVKHVGKTDPGTVFVMNKNIST

Frequently Asked Questions

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