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WBP11 Antibody - N-terminal region : Biotin (ARP46241_P050-Biotin)

Selected Variant

ARP46241_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

WW domain binding protein 11

Gene Aliases

BUG13, FAP90, NPWBP, SIPP1, VCTRL, CFAP90, VCTERL, WBP-11, PPP1R165

Gene ID

51729

Swiss Prot

Q9Y2W2

Accession Number

NP_057396

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human WBP11

Target

WBP11 is a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. WBP11has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus.This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus.

Partner Proteins

TESC; TRAF4; GRB2; FYN; UBC; BMI1; APBB1; WBP4; HECW2; DDX17; RBM5; PPP1CA; DDX5; CTNNBL1; PPP1CC; UPF3B; ZC3H13; CPSF6; SNRPB2; PQBP1; CD2BP2; SF3A2; ITSN1; RTN4IP1; PPP1CB; GIGYF2; MCRS1; PRPF40A; C5orf22; NCK2; TRIP10; NCF1; VIM; SRC; PIK3R1; RUNX1T1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, IP, WB

Purification

Affinity Purified

Sample Type

WBP11 is strongly supported by BioGPS gene expression data to be expressed in HeLa, Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

70kDa

References & Citations

Olsen, J.V., (2006) Cell 127 (3), 635-648

Shipping Conditions

Wet Ice

Protein Length

641

NCBI Gene Symbol

WBP11

NCBI GB Accession Number

WBP11

Host or Source

Rabbit

Protein Name

WW domain-binding protein 11

Nucleotide Accession Number

NM_016312

Peptide Sequence

GRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPK

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