NCAPH Antibody - C-terminal region : Biotin (ARP46227_P050-Biotin)

Product Specifications

Gene Name

Non-SMC condensin I complex, subunit H

Gene Aliases

CAPH, BRRN1, CAP-H, MCPH23

Gene ID

23397

Swiss Prot

Q15003

Accession Number

NP_056156

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human NCAPH

Target

NCAPH is a member of the barr family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization.This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization.

Partner Proteins

SUMO2; UBC; RNF2; HECTD3; NCAPG; ZZEF1; SMC2; SMC4; NCAPD2; GBF1; PLEC; LMNB1; VCP; CDK1; ark1; AURKB; HIST2H2AC; H2AFZ; tat; CAPG

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

NCAPH is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 86%; Horse: 79%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

82kDa

References & Citations

Beausoleil, S.A., (2006) Nat. Biotechnol. 24 (10), 1285-1292

Shipping Conditions

Wet Ice

Protein Length

741

NCBI Gene Symbol

NCAPH

NCBI GB Accession Number

NCAPH

Host or Source

Rabbit

Protein Name

Condensin complex subunit 2

Nucleotide Accession Number

NM_015341

Peptide Sequence

TKDLQRSLPPVMAQNLSIPLAFACLLHLANEKNLKLEGTEDLSDVLVRQG

Subunit

Curated Selection

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