NCAPD2 Antibody - C-terminal region : FITC (ARP46210_P050-FITC)
Product Specifications
Gene Name
Non-SMC condensin I complex, subunit D2
Gene Aliases
CNAP1, CAP-D2, MCPH21, hCAP-D2
Gene ID
9918
Swiss Prot
Q15021
Accession Number
NP_055680
Host
Rabbit
Reactivity
Human, Dog, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human NCAPD2
Target
NCAPD2 is the regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. NCAPD2 may target the condensin complex to DNA via its C-terminal domain.
Partner Proteins
UBC; NCAPG; CCAR2; NCAPH; SMC2; SMC4; TXNL1; RABEP1; PABPC4; RPS5; FLNC; SOX2; CSNK2A1; PAXIP1; PNPT1; NUP153; MEA1; HSPD1; C1QBP; SIRT7; CDK1; RAD21; SIRT3; tat; PARP1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
NCAPD2 is supported by BioGPS gene expression data to be expressed in HeLa
Concentration
0.5 mg/ml
Homology
Dog: 79%; Horse: 93%; Human: 100%; Pig: 92%; Rabbit: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
157kDa
References & Citations
Lee, J.H., (er) Neurogenetics (2008) In press
Shipping Conditions
Wet Ice
Protein Length
1401
NCBI Gene Symbol
NCAPD2
NCBI GB Accession Number
NCAPD2
Host or Source
Rabbit
Protein Name
Condensin complex subunit 1
Nucleotide Accession Number
NM_014865
Peptide Sequence
KAIIDEFEQKLRACHTRGLDGIKELEIGQAGSQRAPSAKKPSTGSRYQPL
Subunit
1
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