MELK Antibody - middle region : Biotin (ARP46207_P050-Biotin)

Product Specifications

Gene Name

Maternal embryonic leucine zipper kinase

Gene Aliases

HPK38

Gene ID

9833

Swiss Prot

Q14680

Accession Number

NP_055606

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human MELK

Target

The protein MELK phosphorylates ZNF622 and may contribute to its redirection to the nucleus. Also it may be involved in the inhibition of spliceosome assembly during mitosis.

Partner Proteins

UBC; YGR054W; Acaca; CSN1S1; MELK; MBP; LMNB1; BABAM1; ZNF622; SF3B1; EIF2S1; CDC5L; PPP1R8; HIST1H1B; CDC25B

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 93%; Guinea Pig: 80%; Horse: 100%; Human: 100%; Rabbit: 87%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

75kDa

References & Citations

Marie, S.K., (2008) Int. J. Cancer 122 (4), 807-815

Shipping Conditions

Wet Ice

Protein Length

651

NCBI Gene Symbol

MELK

NCBI GB Accession Number

MELK

Host or Source

Rabbit

Protein Name

Maternal embryonic leucine zipper kinase

Nucleotide Accession Number

NM_014791

Peptide Sequence

AVKNEEYFMFPEPKTPVNKNQHKREILTTPNRYTTPSKARNQCLKETPIK

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