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PFAS Antibody - N-terminal region : FITC (ARP46181_P050-FITC)

Selected Variant

ARP46181_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Phosphoribosylformylglycinamidine synthase

Gene Aliases

PURL, FGAMS, GATD8, FGARAT, FGAR-AT

Gene ID

5198

Swiss Prot

O15067

Accession Number

NP_036525

Host

Rabbit

Reactivity

Human, Mouse, Cow, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PFAS

Target

Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. PFAS catalyzes the fourth step of IMP biosynthesis. Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis.

Partner Proteins

UBC; SUMO2; TNRC6B; GINS3; ISOC1; BZW2; DCPS; MAT2B; ABHD14A; ERP44; PDCD10; FERMT2; NPEPPS; CNBP; YWHAZ; VCL; RAP1GDS1; PAK2; MSN; LDHB; HSPA9; EIF5; EEF2; ECHS1; DFFA; CKB; CAPN1; SGTA; XIAP; UBR1; USP28; PPP6R3; ZNF593; SEPHS1; CHERP; PRDX6; USP14; UBD

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

PFAS is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 83%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 92%; Rabbit: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

145kDa

References & Citations

Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)

Shipping Conditions

Wet Ice

Protein Length

1338

NCBI Gene Symbol

PFAS

NCBI GB Accession Number

PFAS

Host or Source

Rabbit

Protein Name

Phosphoribosylformylglycinamidine synthase

Nucleotide Accession Number

NM_012393

Peptide Sequence

ESIMSTQESSNPNNVLKFCDNSSAIQGKEVRFLRPEDPTRPSRFQQQQGL

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