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VARS Antibody - middle region : Biotin (ARP46150_P050-Biotin)

Product Specifications

Gene Name

Valyl-tRNA synthetase

Gene Aliases

G7A, VARS, VARS2, NDMSCA

Gene ID

7407

Swiss Prot

P26640

Accession Number

NP_006286

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human VARS

Target

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. VARS belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

CALCOCO2; SUMO2; SART3; STAU1; UBC; EED; CCT4; KNTC1; AIMP1; CCT3; QARS; EEF1G; EEF1D; EEF1B2; FBXO6; YWHAQ; MAPK11; VCAM1; ITGA4; FN1; LARS; CAD; UBD; SHC1; CUL3; CDK2; CHD7; CACNA1A; ATG101; OTUD5; DMWD; EEF1A1; EEF1A2; TRAF6; TFE3; HLA-B; EPB41

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

VARS is strongly supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 86%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

140kDa

References & Citations

Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)

Shipping Conditions

Wet Ice

Protein Length

1264

NCBI Gene Symbol

VARS

NCBI GB Accession Number

VARS

Host or Source

Rabbit

Protein Name

Valine--tRNA ligase

Nucleotide Accession Number

NM_006295

Peptide Sequence

AQRLRERRAASGYPVKVPLEVQEADEAKLQQTEAELRKVDEAIALFQKML

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