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DPP3 Antibody - N-terminal region : Biotin (ARP46138_P050-Biotin)

Product Specifications

Gene Name

Dipeptidyl peptidase 3

Gene Aliases

DPPIII

Gene ID

10072

Swiss Prot

Q9NY33

Accession Number

NP_005691

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DPP3

Target

This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternatively spliced transcript variants have been found for this gene.

Partner Proteins

KEAP1; UBC; NHLRC2; TNFAIP8; NDRG1; TRIP6; SMS; SGTA; PEPD; DLD; ASS1; LIG4; APP; DSTN; TERF2IP; TINF2; POT1; TERF1; SUMO2; HSPA8; ATP5C1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

DPP3 is supported by BioGPS gene expression data to be expressed in 721_B, HeLa, Jurkat, MCF7

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

82kDa

References & Citations

Gudi, R., (2008) Biol. Chem. 389 (2), 163-167

Shipping Conditions

Wet Ice

Protein Length

737

NCBI Gene Symbol

DPP3

NCBI GB Accession Number

DPP3

Host or Source

Rabbit

Protein Name

Dipeptidyl peptidase 3

Nucleotide Accession Number

NM_005700

Peptide Sequence

SRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEE

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