LMNB1 Antibody - middle region: Biotin (ARP46137_P050-Biotin)
Product Specifications
Gene Name
Lamin B1
Gene Aliases
LMN, ADLD, LMN2, LMNB, MCPH26
Gene ID
4001
Swiss Prot
P20700
Accession Number
NP_005564
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human LMNB1
Target
LAMNB1 encodes for one of the two B type proteins of the nuclear lamina, B1. The Vertebrate lamins consist of two types, A and B. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression.The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
POU2F1; SPRTN; UBC; SUMO2; SUMO3; MDM2; EED; ACTR10; NCAPH; ZZEF1; DCTN3; DCTN2; ACTR1A; ACTR1B; PARK2; HECW2; YWHAQ; ADRB2; LMNA; MELK; URB2; FN1; ATF4; SERPINA3; ABCG8; MBIP; GIT2; WHSC1; VCAM1; ITGA4; PRKCB; CDK1; MAGT1; HP1BP3; NCSTN; HNRNPM; EIF6; IL
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
LMNB1 is supported by BioGPS gene expression data to be expressed in SKMEL2
Concentration
0.5 mg/mL
Homology
Cow: 86%; Dog: 100%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 91%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
66kDa
Shipping Conditions
Wet Ice
Protein Length
586
NCBI Gene Symbol
LMNB1
Protein Name
Lamin-B1
Nucleotide Accession Number
NM_005573
Curated Selection
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