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PDK3 Antibody - N-terminal region : HRP (ARP46127_P050-HRP)

Selected Variant

ARP46127_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Pyruvate dehydrogenase kinase, isozyme 3

Gene Aliases

CMTX6, GS1-358P8.4

Gene ID

5165

Swiss Prot

Q15120

Accession Number

NP_005382

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PDK3

Target

PDK3 belongs to the PDK/BCKDK protein kinase family. It contains 1 histidine kinase domain. PDK3 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.

Partner Proteins

APP; UBD; UBC; ICT1; EGFR; DLAT; PDHA1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 85%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 75%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

47kDa

References & Citations

Degenhardt, T., (2007) J. Mol. Biol. 372 (2), 341-355

Shipping Conditions

Wet Ice

Protein Length

406

NCBI Gene Symbol

PDK3

NCBI GB Accession Number

PDK3

Host or Source

Rabbit

Protein Name

[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial

Nucleotide Accession Number

NM_005391

Peptide Sequence

RPSVGLVQSWYMQSFLELLEYENKSPEDPQVLDNFLQVLIKVRNRHNDVV

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