PLK1 Antibody - C-terminal region : Biotin (ARP46120_P050-Biotin)
Product Specifications
Gene Name
Polo-like kinase 1
Gene Aliases
PLK, STPK13
Gene ID
5347
Swiss Prot
P53350
Accession Number
NP_005021
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human PLK1
Target
Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of APC/C inhibitors, and the regulation of mitotic exit and cytokinesis.
Partner Proteins
RAP1GAP; CHFR; KLHL22; BRCA1; BORA; EGFR; UBC; NUAK1; MUS81; FBXO6; PPP6R2; STK3; BUB1B; FZR1; CDC20; CHEK2; TP53BP1; CDCA5; LATS1; CENPU; CDC25C; KLHL21; OFD1; CUL2; Sugt1; KRBA1; HSPA4; PHC2; KLHL9; FLJ20712; RABAC1; TANK; RBX1; VCP; CDH1; APP; STAG2; N
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
68kDa
References & Citations
Yamashiro, S., (2008) Dev. Cell 14 (5), 787-797
Shipping Conditions
Wet Ice
Protein Length
603
NCBI Gene Symbol
PLK1
NCBI GB Accession Number
PLK1
Host or Source
Rabbit
Protein Name
Serine/threonine-protein kinase PLK1
Nucleotide Accession Number
NM_005030
Peptide Sequence
KRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSRSASNRLKAS
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