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GSDME Antibody - C-terminal region: FITC (ARP46106_T100-FITC)

Product Specifications

Gene Name

Gasdermin E

Gene Aliases

DFNA5, ICERE-1

Gene ID

1687

Swiss Prot

A4FVA8

Accession Number

AAI25067

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human DFNA5

Target

Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.

Partner Proteins

UBC; EGFR; PTN

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

DFNA5 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/mL

Homology

Cow: 85%; Dog: 77%; Guinea Pig: 83%; Human: 100%; Rat: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

47kDa

Shipping Conditions

Wet Ice

Protein Length

437

NCBI Gene Symbol

GSDME

Protein Name

Gasdermin-E

Nucleotide Accession Number

NM_001127453

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