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ATIC Antibody - N-terminal region : Biotin (ARP46095_T100-Biotin)

Product Specifications

Gene Name

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

Gene Aliases

PURH, AICAR, AICARFT, IMPCHASE, HEL-S-70p

Gene ID

471

Swiss Prot

P31939

Accession Number

NP_004035

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ATIC

Target

ATIC is a bifunctional protein requiring dimerization for transformylase activity.

Partner Proteins

UBC; NEDD8; SUMO1; ASB6; TATDN1; NSFL1C; OGFOD1; STK26; ISOC1; MCTS1; PROSC; PAPSS1; NAE1; YWHAE; UBA1; PTMA; PAFAH1B1; MYO1E; MSN; IPO5; FH; CTH; CAPN2; AHCY; GMDS; TARDBP; TYMS; TXN; SUMO2; RBBP6; OXCT1; CRK; CLNS1A; CDK2; ISG15; SIRT7; EGFR; ATIC; CMBL

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Sample Type

ATIC is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

64kDa

References & Citations

Geraghty, K.M., (2007) Biochem. J. 407 (2), 231-241

Shipping Conditions

Wet Ice

Protein Length

592

NCBI Gene Symbol

ATIC

NCBI GB Accession Number

ATIC

Host or Source

Rabbit

Protein Name

Bifunctional purine biosynthesis protein PURH

Nucleotide Accession Number

NM_004044

Peptide Sequence

YVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKG

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