PPAT Antibody - C-terminal region : Biotin (ARP46080_P050-Biotin)

Product Specifications

Gene Name

Phosphoribosyl pyrophosphate amidotransferase

Gene Aliases

GPAT, PRAT, ATASE

Gene ID

5471

Swiss Prot

Q06203

Accession Number

NP_002694

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human PPAT

Target

PPAT is a member of the purine/pyrimidine phosphoribosyltransferase family. This protein is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthesis. Its gene and PAICS/AIRC, a bifunctional enzyme catalyzing steps six and seven in the purine nucleotide biosynthesis pathway, are located in close proximity on chromosome 4.The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. This protein is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthesis. This gene and PAICS/AIRC, a bifunctional enzyme catalyzing steps six and seven in the purine nucleotide biosynthesis pathway, are located in close proximity on chromosome 4.The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. This protein is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthesis. This gene and PAICS/AIRC, a bifunctional enzyme catalyzing steps six and seven in the purine nucleotide biosynthesis pathway, are located in close proximity on chromosome 4.

Partner Proteins

FAM96B; CIAO1; FAM114A1; PARVA; CARM1; RANBP3; TROVE2; RSU1; MEA1; ILK; HSPA4; GART; CARS; MMS19; EPT1; ATXN1; SMURF1; MCM3; UBC

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

PPAT is strongly supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Dog: 92%; Horse: 77%; Human: 100%; Mouse: 86%; Rat: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.