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CTPS Antibody - N-terminal region : FITC (ARP46069_T100-FITC)

Product Specifications

Gene Name

CTP synthase

Gene Aliases

CTPS, GATD5, IMD24

Gene ID

1503

Swiss Prot

P17812

Accession Number

NP_001896

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CTPS

Target

The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis.The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis. The region to which the CTPS gene has been mapped is the location of breakpoints involved in several tumor types.The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis. The region to which the CTPS gene has been mapped is the location of breakpoints involved in several tumor types.

Partner Proteins

UBC; CTPS1; TUBGCP3; AURKA; SUMO2; SUMO3; SUMO1; NEDD8; DCTPP1; GINS3; UBA6; UBXN1; PAPSS1; VCL; UBA1; PPP5C; PKM; DFFA; CS; CLNS1A; ACO1; YWHAQ; MYC; RBM28; POLR1C; FBXO6; CAND1; COPS5; CUL1; CUL2; CUL3; CUL4B; CUL5; CDK2; ARRB2; RAD21; PSMA3; YWHAG; TRA

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

CTPS1 is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

67kDa

References & Citations

Han, G.S., (2005) J. Biol. Chem. 280 (46), 38328-38336

Shipping Conditions

Wet Ice

Protein Length

591

NCBI Gene Symbol

CTPS1

NCBI GB Accession Number

CTPS1

Host or Source

Rabbit

Protein Name

CTP synthase 1

Nucleotide Accession Number

NM_001905

Peptide Sequence

SMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELR

Frequently Asked Questions

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