MAP4K1 Antibody - N-terminal region : Biotin (ARP46044_P050-Biotin)
Product Specifications
Gene Name
Mitogen-activated protein kinase kinase kinase kinase 1
Gene Aliases
HPK1
Gene ID
11184
Swiss Prot
A8MWC4
Accession Number
NP_001036065
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4K1
Target
MAP4K1 belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily. MAP4K1 may play a role in the response to environmental stress. It appears to act upstream of the JUN N-terminal pathway. MAP4K1 may play a role in hematopoietic lineage decisions and growth regulation.
Partner Proteins
FBXW7; FBXW8; MAP4K1; UBC; SKP1; PPP4C; RBX1; CUL7; TMEM101; HSP90AA1; NCK1; LRRK1; SPRY1; GRAP2; COPS5; DBNL; DAPP1; BLNK; MAP3K7; LAT; CRKL; LCP2; HCLS1; CASP3; SHC1; SYK; MAP3K11; ABL1; LYN; CRK; EGFR; GRB2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
MAP4K1 is strongly supported by BioGPS gene expression data to be expressed in 721_B
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Zebrafish: 83%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
90kDa
References & Citations
Brenner, D., (2007) Blood 110 (12), 3968-3977
Shipping Conditions
Wet Ice
Protein Length
821
NCBI Gene Symbol
MAP4K1
NCBI GB Accession Number
MAP4K1
Host or Source
Rabbit
Nucleotide Accession Number
NM_001042600
Peptide Sequence
VHPLRVLFLMTKSGYQPPRLKEKGKWSAAFHNFIKVTLTKSPKKRPSATK
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