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SMC2 Antibody - N-terminal region : Biotin (ARP46043_P050-Biotin)

Product Specifications

Gene Name

Structural maintenance of chromosomes 2

Gene Aliases

CAPE, CAP-E, SMC-2, SMC2L1

Gene ID

10592

Swiss Prot

O95347

Accession Number

AAH03396

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SMC2

Target

SMC2 is the central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

Partner Proteins

UBC; RPA3; RPA2; RPA1; NCAPG; CCAR2; NCAPH; SSSCA1; SMC4; NCAPD2; PLEC; CDK9; FBXO6; EGFR; SOX2; GULP1; ABCC5; PAXIP1; SMC1A; UBD; NEDD8; SUMO2; NCAPG2; NCAPH2; NCAPD3; RAD21; LIG4; HIST2H3C; DISC1; TRAF3IP1; HIST2H2BE; HIST2H2AC; H2AFZ; MYC; tat; DNMT3B

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

SMC2 is strongly supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 86%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

32kDa

Shipping Conditions

Wet Ice

Protein Length

289

NCBI Gene Symbol

SMC2

NCBI GB Accession Number

SMC2

Host or Source

Rabbit

Protein Name

Structural maintenance of chromosomes protein 2

Nucleotide Accession Number

NM_001042550

Peptide Sequence

ISNLSQVRASNLQDLVYKNGQAGITKASVSITFDNSDKKQSPLGFEVHDE

Frequently Asked Questions

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