KYNU Antibody - C-terminal region : Biotin (ARP46037_P050-Biotin)
Product Specifications
Gene Name
Kynureninase
Gene Aliases
KYNUU, VCRL2
Gene ID
8942
Swiss Prot
Q16719
Accession Number
NP_003928
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human KYNU
Target
Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway.Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene.Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene.
Partner Proteins
LDHAL6B; BCCIP; CNDP2; NAGK; CHORDC1; C11orf58; NDRG1; GDA; SMS; RPS6KA1; PEPD; MVD; LDHA; GSR; GNS; CSE1L; ADSS; LYN; UBC; PALM2; SMEK2; SSU72; SIRT1; NUP210; SEC23IP; COIL; TPM3; SMARCD2; SGTA; PPM1G; ASNS
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Sample Type
KYNU is supported by BioGPS gene expression data to be expressed in HepG2
Concentration
0.5 mg/ml
Homology
Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 86%; Yeast: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
52kDa
References & Citations
Suzuki, Y., Gene 200 (1-2), 149-156 (1997)
Shipping Conditions
Wet Ice
Protein Length
465
NCBI Gene Symbol
KYNU
NCBI GB Accession Number
KYNU
Host or Source
Rabbit
Protein Name
Kynureninase
Nucleotide Accession Number
NM_003937
Peptide Sequence
LAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP
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