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GUCY1B1 Antibody - N-terminal region : Biotin (ARP46012_P050-Biotin)

Product Specifications

Gene Name

Guanylate cyclase 1 soluble subunit beta 1

Gene Aliases

GUCB3, GC-SB3, GUC1B3, GUCSB3, GUCY1B3, GC-S-beta-1

Gene ID

2983

Swiss Prot

Q02153

Accession Number

NP_000848

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GUCY1B3

Target

This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate) . The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants.

Partner Proteins

APP; STUB1; UBC; AGAP1; GUCY1A2; HSP90AA1; NOS3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

GUCY1B3 is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

70kDa

References & Citations

Slavov, D., (2006) Int. J. Impot. Res. 18 (5), 432-437

Shipping Conditions

Wet Ice

Protein Length

619

NCBI Gene Symbol

GUCY1B1

NCBI GB Accession Number

GUCY1B1

Host or Source

Rabbit

Protein Name

Guanylate cyclase soluble subunit beta-1

Nucleotide Accession Number

NM_000857

Peptide Sequence

LIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVV

Subunit

Beta-1

Frequently Asked Questions

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